New treatment for breast cancer developed in Finland used in pilot clinical study by Philips and University Medical Center

First patient in pilot study is already treated. The technology makes it possible to operating without making any incisions – offering patients an outpatient procedure with faster recovery and lower complication. The ultimate goal is to advance cancer care.
Helsinki, Finland ? The University Medical Center Utrecht and Philips announced that they have started a pilot clinical study to evaluate a new treatment for breast cancer based on a technology called MR-guided High Intensity Focused Ultrasound (MR-HIFU). The technology is developed in Helsinki, Finland, by the team lead by Falko Busse, General Manager MR-Therapy at Philips Healthcare.
Since 2005, the highly specialized multi-disciplinary team in Finland is developing innovative, minimally invasive therapy solutions for multiple medical conditions based on MR-HIFU technology. The Sonalleve MR-HIFU system for treatment of uterine fibroids was introduced to the market about three years ago. A year later the first application related to cancer was released, the treatment of painful bone metastasis with MR-HIFU. Approximately 50 Sonalleve MR-HIFU systems are in use in America, Europe and Asia. In Nordic MR-HIFU systems are available in Denmark and Norway.
Innovative technologies are developed in close collaboration with local and international clinical partners.The pilot study into MR-HIFU treatment combines the clinical expertise and medical technology know-how of UMC Utrecht and Philips. To facilitate this pilot study, Philips has built a dedicated investigational system optimized for the anatomy of the female breast. The first patient in the study has already been treated using the system.
?This new pilot study targets patients with small breast tumors that have not metastasized; these patients belong to a group that encompasses approximately a quarter of all breast cancer patients in the Netherlands?, says Maurice van den Bosch, MD, interventional radiologist and research leader at the University Medical Center Utrecht. He continues:
?An important aspect of the MR-HIFU technique is that the skin stays completely intact, since everything can be done non-invasively, operating without making any incisions.?
MR-HIFU has emerged as a technology with the potential to non-invasively destroy tumors by heating them up while they are still inside the body. The technique is capable of achieving tissue temperatures in excess of 65 degrees Celsius, high enough to kill tumor cells without damaging the surrounding tissue.
Magnetic Resonance (MR) imaging provides real-time imaging of soft tissue structures so that the HIFU beam can be accurately focused onto the tumor. It also spatially maps local tissue temperatures in order to provide real-time feedback for controlling the applied temperature profiles.
?MR-guided HIFU could become a very powerful tool in the hands of physicians?, says Falko Busse, General Manager MR-Therapy at Philips Healthcare. ?The benefits of its non-invasiveness have already been shown in the treatment of benign tumors of the uterus, offering patients an outpatient procedure with faster recovery and lower complication rates than surgical removal. We are now further developing this technology with the ultimate goal to advance cancer care.?
In this study the MR-HIFU treatment is being carried out under local anesthetic or sedation. Following this treatment, a conventional surgical procedure will be performed to verify the precision of the treatment. The initial aim of the study is to assess the image quality achieved by the MR-HIFU system as well as the safety and precision of the technique in this particular application.

For media inquiries, please contact:

Käthryn Cars
Philips Corporate Communications Nordic
Tel: +46 (0) 708 32 20 22
E-mail: [email protected]

Harma Plaggemars
University Medical Center Utrecht
Tel. +31 6 42 95 2502
E-mail: [email protected]

About the MR-HIFU pilot study
The pi0lot study into MR-HIFU treatment combines the clinical expertise and medical technology know-how of UMC Utrecht and Philips respectively. The study is part of a larger Dutch research program with a total budget of EUR 11 million. The Center for Translational Molecular Medicine (CTMM) – a public-private partnership for Netherlands-based translational research – is the main funder of the program. Philips and the Netherlands Organization for Health Research and Development (ZonMw) are also contributors.
About the University Medical Center Utrecht (UMC Utrecht)
The University Medical Center Utrecht is one of the largest public healthcare institutions in the Netherlands. With almost 11,000 employees, it is constantly building on the provision of good healthcare services based on knowledge and people. The UMC Utrecht strives to be a leading international university medical center where knowledge about health, disease and healthcare is generated, tested, shared and applied. UMC Utrecht forms part of the Netherlands Federation of University Medical Centers (‘Nederlandse Federatie van Universitair Medische Centra, NFU’). The NFU is a partnership that brings together the eight university medical centers (UMCs) in the Netherlands. Visit the site for more information about the NFU. More news about the UMC Utrecht can be found at:
Om Royal Philips Electronics
Nederlandske Royal Philips Electronics (NYSE: PHG, AEX: PHI) er et vidtspennende konsern innen helse- og livsstilsprodukter, med fokus p? ? forbedre menneskers liv gjennom innovasjoner. Som en ledende akt?r innen helse, livsstil og lys, integrerer Philips teknologi og design i brukervennlige l?sninger med mennesket i sentrum, basert p? grunnleggende kunnskap om forbrukeren og i samsvar med varemerkel?ftet ?sense and simplicity?. Hovedkontoret ligger i Nederland og Philips har 122 000 ansatte i mer enn 100 land verden over. Med en omsetning p? EUR 22,6 mrd. i 2011, er selskapet markedsledende innen medisinsk diagnostikk, akutt behandling og pasientoverv?kning, energieffektive- og nye lysl?sninger samt forbrukerelektronikk og livsstilsprodukter for personlig pleie. I tillegg har Philips en sterk posisjon innen barbering og annen velv?re for menn, b?rbar underholdning og tannpleie. 0000Send som e-post
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